The NCCN also reports that almost two-thirds of sufferers with recurring cancers or advanced stages of cancer experience discomfort. Pain control is possible, for those suffering from cancer even, and it can give a patient a better standard of living. Pain in cancer individuals is most a result of the cancer itself often, but it can derive from a particular treatment sometimes, such as for example radiation therapy. Pain can be relieved through several methods.Other Analyses The methods that we used for gene-expression arrays, polymerase-chain-response and sequencing analyses, protein immunoprecipitation, and Western blotting are described in detail in the Supplementary Appendix, available with the entire text of the article at NEJM.org. All digital images were enhanced for lighting and contrast with the use of Photoshop Elements 5.0 . Results Clinical Description On ultrasonographic imaging of Fetus 1 and Fetus 2, we noticed an unusual cyst in the cranial region, a large defect in the craniofacial area, an omphalocele, and immotile and hypoplastic limbs . Figure 1C through 1F present the fetuses after the pregnancies were terminated because of these severe malformations.