Alcoholism or Alcohol abuse can be of because of many elements including genetics, friends circle, cultural environment, & mental health of a person. People who are carefully associated with people who are weighty drinkers or anyone who has history of Family addiction are receiving indulged in drinking complications. Since drinking is approved by many cultures including ours so it is very challenging to understand the drinking habit of a person be it a public drinking or problem drinking. But there are few symptoms which clarify the consuming problems like – * Taking alcoholic beverages for relaxing or sense better from any melancholy * Didn’t recall anything after drinking * Telling a lie to others * Sense ashamed for his/her drinking behaviors.However, the consistent effects in our two trials reinforce our results and suggest that there was no difference in outcomes among clopidogrel-treated individuals in subgroups defined relating to loss-of-function carrier position. Subgroup Analyses Among the genotyped participants in the CURE trial, the effects of our analyses of the consequences of clopidogrel as compared with placebo were constant across subgroups defined according to loss-of-function carrier status, whether participants underwent PCI . Even though only 736 patients who received stents were included in the genetic evaluation, there is a significant treatment effect of clopidogrel on the first composite primary final result among loss-of-function allele carriers . A similar treatment impact was observed among noncarriers , and there is no proof an interaction between carrier status and study treatment regarding either the initial or the second composite primary outcome .