Usually, a number of factors contribute to the advancement of a problem with alcohol. Social factors such as the influence of family, peers, and culture, and the availability of alcohol, and emotional factors such as elevated levels of stress, inadequate coping mechanisms, and reinforcement of alcohol make use of from other drinkers can contribute to alcoholism. Also, the elements adding to initial alcohol use may vary from those keeping it, once the disease develops. While it may not be causative, twice as many men are alcohol dependent. Statistics show alcohol problems are highest among adults aged 18-29, and those who start drinking before age 21 are four times much more likely to develop alcohol dependence and to be engaged in alcohol-related violence..We used rates of breast cancers from U.S.21 and Polish22 registries, as appropriate. Model Discrimination Using receiver-operating-feature curve analysis, we calculated the area under the curve , also known as a concordance statistic, to assess discrimination. Each point on the ROC curve shows the effect of a rule for turning a risk estimate into a prediction of the development of breast malignancy in a female. The y axis of the ROC curve may be the true positive rate or sensitivity . The x axis displays the false positive price . The certain region beneath the ROC curve, the AUC, measures how well the model discriminates between case subjects and control subjects.