Surprised by this phenomenon, UCI experts conducted a series of studies in rodents to determine whether nicotine may interact with a few of the other 4,000 components of tobacco smoke to enhance addictiveness. Adolescent and adult male rats had been tested in an operation where each nasal area poke by the rodents delivered acetaldehyde or nicotine, a combination of both medications, or saline. Adolescent animals quickly learned to self-administer the nicotine-acetaldehyde combination more than saline or either drug alone significantly.The buzz about the beautiful little brains of big insects A long tradition of studying invertebrates to understand about anxious systems has contributed greatly to our knowledge of the functional firm, development and evolution of the intricate networks and the neural mechanisms that are at the root of behavior. Insects in particular offer powerful experimental model systems. Today, the most prominent example is the fruit fly, whose genomic and genetic advantages attract many researchers, but whose little size is usually limiting for a few kinds of research.